BDBM423299 US10501452, Compound 5

SMILES CN1CCc2ccc(OCCCN3CCC(CC3)c3noc4cc(F)ccc34)cc2C1=O

InChI Key InChIKey=RDGPIFCCGRDXMY-UHFFFAOYSA-N

Data  22 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 423299   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423299(US10501452, Compound 5)
Affinity DataKi:  0.100nMAssay Description:5-HT2A:(1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423299(US10501452, Compound 5)
Affinity DataKi:  0.650nMAssay Description:Displacement of [3H]ketanserin from rat cerebral cortex 5HT2A receptor measured after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM423299(US10501452, Compound 5)
Affinity DataIC50:  46nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium flux incubated for 60 mins at 37 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed